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Sounding Out the Blood-Brain Barrier

  • Hynynen, Kullervo Ph.D.

  • From Sunnybrook Research Institute and the Department of Medical Biophysics and the Institute of Biomedical Engineering, University of Toronto — both in Toronto.

Disclosure forms as provided by the author are available with the full text of this editorial at NEJM.org.

New England Journal of Medicine 390(1):p 82-85, January 4, 2024. | DOI: 10.1056/NEJMe2311358

The Blood-Brain Barrier and Alzheimer's Disease

This editorial describes the science behind a trial involving a breach of the blood-brain barrier to deliver drugs to the brain.

Corresponding Article

Ultrasound Blood-Brain Barrier Opening and Aducanumab in Alzheimer's Disease

  • Rezai, Ali R. M.D.
  • D'Haese, Pierre-Francois Ph.D.
  • Finomore, Victor Ph.D.
  • Carpenter, Jeffrey M.D.
  • Ranjan, Manish M.B., B.S.
  • Wilhelmsen, Kirk M.D.
  • Mehta, Rashi I. M.D.
  • Wang, Peng Ph.D.
  • Najib, Umer M.D.
  • Teixeira, Camila Vieira Ligo Ph.D.
  • Arsiwala, Tasneem Ph.D.
  • Tarabishy, Abdul M.D.
  • Tirumalai, Padmashree Ph.D.
  • Claassen, Daniel O. M.D.
  • Hodder, Sally M.D.
  • Haut, Marc W. Ph.D.
New England Journal of Medicine 390(1):p 55-62, January 4, 2024. | DOI: 10.1056/NEJMoa2308719
Copyright © 2024 Massachusetts Medical Society. All rights reserved.
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